The Study Findings table contains information on the genetic findings of a particular NESHIE or CP genetic study. Variants with statistically-significant associations with NESHIE or CP have p-values < 0.05. Odds ratio values quantify the strength of association of a variant allele with NESHIE or CP.
Paper: Wu et al., 2009
DOI: 10.1002/ana.21766
Study population description: Caucasian, African, Hispanic, Asian, Other; 250 infants with CP in the Kaiser Medical Care Programme of Northern California and 652 controls
Regional classification: Europe, Africa, America, East Asia
Sequencing or genotyping methods: Amplification of gene DNA and genotyping using polymerase-chain reaction based methods
| Variant | Reported allele or genotype | Condition | Condition description | Disease status | Odds ratio | P value |
|---|---|---|---|---|---|---|
| rs1800795 | C allele | CP | None | Susceptibility | 1.400 | 0.03000000 |
| rs1800795 | CC genotype | CP | None | Susceptibility | 2.600 | 0.00100000 |
| rs1800795 | CC genotype | CP | Caucasian | Susceptibility | None | 0.03000000 |
| rs1800795 | GC + CC genotype | CP | None | Susceptibility | 1.600 | 0.02000000 |
| rs1800795 | C allele | CP | None | Susceptibility | 1.400 | 0.03000000 |
| rs1800795 | CC genotype | CP | Controlling for race | Susceptibility | 2.400 | 0.00400000 |
| rs1800795 | CC genotype | CP | Controlling for race; clinical chorioamnionitis | Susceptibility | 4.600 | <0.00010000 |
| rs1800795 | CC genotype | CP | Controlling for race; maternal age >= 35 | Susceptibility | 2.500 | <0.00010000 |
| rs1800795 | CC genotype | CP | Controlling for race; male sex | Susceptibility | 1.500 | 0.02000000 |