The Study Findings table contains information on the genetic findings of a particular NESHIE or CP genetic study. Variants with statistically-significant associations with NESHIE or CP have p-values < 0.05. Odds ratio values quantify the strength of association of a variant allele with NESHIE or CP.
Paper: Torres-Merino et al., 2019
DOI: 10.1007/s12035-018-1178-6
Study population description: Mexican; 48 patients with a history of perinatal asphyxia, low Apgar score (< 7 at 5 min), stage II or III Sarnat score in the neonatal period, and no records of chorioamnionitis or maternal infection and 57 control children
Regional classification: America
Sequencing or genotyping methods: Polymerase chain reaction amplification of gene regions followed by polymerase chain reaction-RFLP assay for rs16944 polymorphism. Validation of rs16944 polymorphism using a TaqMan allelic discrimination test.
| Variant | Reported allele or genotype | Condition | Condition description | Disease status | Odds ratio | P value |
|---|---|---|---|---|---|---|
| rs16944 | TT genotype | CP | NESHIE | Susceptibility | 2.633 | 0.01890000 |