The Study Findings table contains information on the genetic findings of a particular NESHIE or CP genetic study. Variants with statistically-significant associations with NESHIE or CP have p-values < 0.05. Odds ratio values quantify the strength of association of a variant allele with NESHIE or CP.
Paper: Gibson et al., 2006
DOI: 10.1016/j.ajog.2006.01.093
Study population description: Causasian; 448 children with CP born in South Australia from the South Australian Cerebral Palsy Register and 883 controls
Regional classification: Oceania
Sequencing or genotyping methods: Genotyping of MBL gene polymorphisms using heteroduplex genotyping methods. Genotyping of TNF gene polymorphisms using amplification refractory mutation system-polymerase chain reaction genotyping methods
| Variant | Reported allele or genotype | Condition | Condition description | Disease status | Odds ratio | P value |
|---|---|---|---|---|---|---|
| rs1800629 | GA genotype | CP | Quadriplegia, gestational age >= 37 weeks | Susceptibility | 1.820 | 0.02000000 |
| rs1800629 | GA + AA genotype | CP | Hemiplegia, gestational age < 32 weeks | Susceptibility | 2.380 | 0.03000000 |