The Study Findings table contains information on the genetic findings of a particular NESHIE or CP genetic study. Variants with statistically-significant associations with NESHIE or CP have p-values < 0.05. Odds ratio values quantify the strength of association of a variant allele with NESHIE or CP.
Paper: Kremer and Grosso, 2004
DOI: 10.1111/j.1399-0004.2004.00373.x
Study population description: Argentine; 11 Argentine patients diagnosed with HIE and their mothers, 8 siblings and 9 fathers, 85 Argentine controls of mixed ancestry
Regional classification: America
Sequencing or genotyping methods: Genotyping using polymerase chain reaction-restriction fragment length polymorphism methods
| Variant | Reported allele or genotype | Condition | Condition description | Disease status | Odds ratio | P value |
|---|---|---|---|---|---|---|
| rs1801133 | A allele | NESHIE | Associated with mothers of affected children with CP | Susceptibility | None | <0.05000000 |
| rs1801133 | A allele | NESHIE | Associated with increased levels of plasma homocysteine after methionine loading in mothers of CP patients | Susceptibility | None | <0.05000000 |