Study Findings

The Study Findings table contains information on the genetic findings of a particular NESHIE or CP genetic study. Variants with statistically-significant associations with NESHIE or CP have p-values < 0.05. Odds ratio values quantify the strength of association of a variant allele with NESHIE or CP.

Paper: Gabriel et al., 2016

DOI: 10.2147/JIR.S103697

Study population description: Brazilian; 50 preterm and term newborns with HIE and PVL and 50 controls

Regional classification: America

Sequencing or genotyping methods: Genotyping using polymerase chain reaction-restriction fragment length polymorphism methods

Variant	Reported allele or genotype	Condition	Condition description	Disease status	Odds ratio	P value
rs1799964	TT genotype	NESHIE	Reduced periventricular leukomalacia risk	Severity	0.408	0.04400000
rs16944	CT + TT genotype	NESHIE	Periventricular leukomalacia	Severity	23.120	0.00300000
rs16944	CC genotype	NESHIE	Reduced periventricular leukomalacia risk	Severity	0.043	0.00300000
rs1800896	GG genotype	NESHIE	Reduced periventricular leukomalacia risk	Severity	0.074	<0.00010000
rs1800896	G allele	NESHIE	Reduced periventricular leukomalacia risk	Severity	0.510	0.03000000
rs1800896	GA genotype	NESHIE	Periventricular leukomalacia	Severity	13.500	<0.00010000
rs1800896	A allele	NESHIE	Periventricular leukomalacia	Severity	1.962	0.03000000
rs1799964	TC genotypes	NESHIE	Periventricular leukomalacia	Susceptibility	2.495	0.04300000
rs1799964	TC + CC genotype	NESHIE	Periventricular leukomalacia	Susceptibility	2.471	0.04400000
rs16944	CT + TT genotype	NESHIE	Periventricular leukomalacia	Susceptibility	23.120	0.00300000