The Study Findings table contains information on the genetic findings of a particular NESHIE or CP genetic study. Variants with statistically-significant associations with NESHIE or CP have p-values < 0.05. Odds ratio values quantify the strength of association of a variant allele with NESHIE or CP.
Paper: Esih et al., 2021_2
Study population description: Slovenian; 43 newborns with moderate and severe HIE registered in the electronic database of the neonatal intensive care unit at the University Children’s Hospital Ljubljana
Regional classification: Europe
Sequencing or genotyping methods: Genotyping using fluorescent-based competitive allele-specific polymerase chain reaction assay
| Variant | Reported allele or genotype | Condition | Condition description | Disease status | Odds ratio | P value |
|---|---|---|---|---|---|---|
| rs2043211 | T allele | NESHIE | Lower epilepsy risk in carriers of two normal IL1B rs16944 alleles | Severity | 0.030 | 0.01900000 |
| rs16944 | T allele | NESHIE | Higher epilepsy risk only in carriers of at least one polymorphic CARD8 rs2043211 | Severity | 13.330 | 0.04400000 |