The Study Findings table contains information on the genetic findings of a particular NESHIE or CP genetic study. Variants with statistically-significant associations with NESHIE or CP have p-values < 0.05. Odds ratio values quantify the strength of association of a variant allele with NESHIE or CP.
Paper: Pavlov, et al., 2023
DOI: 10.3390/biomedicines11102795
Study population description: Croatian; 132 retrospective HIE cases treated at the University Hospital Split, Children’s Hospital, Department for Gynecology and Obstetrics, and Department of Neonatology
Regional classification: Europe
Sequencing or genotyping methods: Genotyping using a real-time TaqMan polymerase chain reaction assay
| Variant | Reported allele or genotype | Condition | Condition description | Disease status | Odds ratio | P value |
|---|---|---|---|---|---|---|
| rs6103 | CC genotype | NESHIE | None | Susceptibility | 3.800 | 0.01300000 |
| rs1137933 | AG genotype | NESHIE | Higher risk of more severe magnetic resonance imaging findings | Severity | 7.100 | 0.02800000 |